Dr Tarsem Sahota

• Development of artificial pancreas
• Delivery of insulin by self regulation
• Structure and behaviour of insulin in solution
• Polymerisation and covalent structures of proteins and polysaccharides, e.g. lectins and glucose polymers
• In vivo studies
• Development of a triggered dermatological formulation for the treatment of psoriasis
• Physiological parameters for exercise in diabetes.

• Department of Diabetes and Endocrinology, University Hospitals of Leicester NHS Trust
• National Physical Laboratory
• IOCT, De Montfort University
• Renfrew Group, Leicester

Click here for a full listing of Tarsem Sahota's publications and outputs.

Taylor, M. J., S. Tanna, et al. (2008). "UV Cross-Linked Dextran Methacrylate - Concanavalin A Methacrylamide Gel Materials for Self-Regulated Insulin Delivery." Drug Dev Ind Pharm 34(1): 73-82.

Taylor M J, Tanna, S., Sahota, T. S. et al “Glucose-sensitive gel rheology of dextran-concanavalin A mixtures suitable for self-regulating insulin delivery” Pharmaceutical Development and Technology 15(1):80-8, 2010.

Taylor M J, Sahota, T. S. “In vivo study of a polymeric glucose sensitive insulin delivery system using a rat model” Journal of Pharmaceutical Sciences, 9, 10, 4215-4227 2010.

S., Sahota, Sawicka,  Taylor M J, Tanna, , T. S. “Effect of varying molecular weight of dextran on acrylic derivatised dextran and concanavalin A glucose-responsive materials for closed-loop insulin delivery” Drug Development and Industrial Pharmacy, 2011, Mar;37(3):351-8.

• Insulin physico-chemistry
• Diabetes control
• Drug delivery
• Rheometry (viscosity of gels and sols)
• Engineering and design of devices for drug delivery
• Physiological parameters for exercise in diabetes.

Posters
Taylor, M. & Sahota, T. Glucose-sensitive insulin delivery in vivo - an artificial pancreas? (Poster) 3rd International Conference on Advanced Treatments and Technologies (ATTD) Basel Feb 2010

Sahota T.S. & Taylor M.J. Competitive displacement of blue dextran by cibacron blue in dextran albumin gels? (Poster) Intern. Symp. Control. Rel. Bioact. Mater, Controlled Release Society, Inc. Portland, Oregon 2010

Sahota T.S. & Taylor M.J. Closed Loop Delivery in the Pig (accepted poster) Controlled Release Society Annual Symposium, Quebec, Canada 2012

• Polymer synthesis
• Rheology
• HPLC
• Pressure measurements
• Diabetes
• Focus groups and survey design
• GPC

Co-Investigator on the following grants:

• NEAT funding (£278k)
• HFCE matched funding (25k)
• Edith Murphy Foundation 2008 (£50k)
• Edith Murphy Foundation 2011 (£200k)
• Lachesis (£5k)