Dr Mounir Maafi

Job: Senior Lecturer

Faculty: Health and Life Sciences

School/department: Leicester School of Pharmacy

Address: De Montfort University, The Gateway, Leicester, LE1 9BH.

T: +44 (0)116 257 7704

E: mmaafi@dmu.ac.uk

W: https://www.dmu.ac.uk/hls

 

Personal profile

Mounir Maafi is a senior lecturer at the Leicester School of Pharmacy and he is an active researcher in drugs photostability and stabilisation. He holds an engineer degree from the National Institute of Industrial Chemistry (Algeria), a DEA in Spectrochemical Analysis of Organic and Biological Materials from Paris 6 - Paris 7 Universities, and a PhD in physical/analytical chemistry from Paris 7 University. Dr Maafi has held several Research Fellow/postdoctoral positions including at the Institute of Topology and System Dynamics (Paris, France), the Department of Analytical Chemistry (Badajoz, Spain), the Karolinska Institute at the Karolinska Hospital (Stockholm, Sweden), and at the University of Glamorgan (Cardiff, UK). He has also held university teaching positions as an Associate Professor at Marne La Vallée University, Paris 7 university and CPCM-Paris in France, and at University of Glamorgan at Cardiff. Dr Maafi is an editor for E-Journal of chemistry and a referee for several journals. He speaks five languages and hopes to learn a few more.

Research group affiliations

Chemistry for Health

Key research outputs

The potential of AB(1) systems for direct actinometry. Diarylethenes as successful actimometers for the visible range. M Maafi, Phys Chem Chem Phys, 2010 12 (40), pp 13248-13254.

A mathematical analysis and elucidation of AB(2k,1φ) thermophotochromic kinetics. An analytical solution using pure kinetic data and considering as unknown The rate constants, quantum yield and both species’ spectra. M Maafi, R G Brown, Int J Chem Kinet, 41(4), pp 255 – 264 2009.

Kinetic analysis and kinetic elucidation options for AB(1k,2) systems. New Spectrokinetic methods for photochromes. M Maafi, R G Brown. Photochem Photobiol Sci, 7, pp 1360 – 1372 2008.

Spectrokinetic Methods for the Investigation of Photochromic and Thermo-Photochromic Spiropyrans. M Maafi, Molecules 13(9), pp 2260-2302 2008.

Comment on “Photokinetic methods: A mathematical analysis of the rate equations in photochromic systems; by G Ottavi, F Ortica, G Favaro, Int J Chem Kinet, 1999 31, 303-313.” M Maafi, Int J Chem Kinet, 40, pp 524-525 2008.

A Fundamental system of equation to describe ABC(3k,6 dynamics. Contribution to the elucdation of [2H]-naphthopyran kinetics. M Maafi, R G Brown, Int J Chem Kinet, 40, pp 268-281 2008.

The kinetic model for AB(1) systems. A Closed-form integration of the differential equation with a variable photokinetic factor. M Maafi, R G Brown, J Photochem Photobiol A:Chem, 187, pp.319-324 2007.

Research interests/expertise

  • Modelling photoreactions and spectrokinetics
  • Thermochromes and photochromic materials
  • Drug phodegradation and stabilisation
  • Drug specials
  • Anticancer, synthetic hormone and cardiovascular drugs
  • Cyclodextrin superamolecular systems
  • Drug delivery systems
  • Development of analytical methods for soil analysis.

Areas of teaching

  • Spectroscopy/spectrochmistry
  • Analytical chemistry
  • Physical chemistry and thermodynamics
  • Drug formulation and stability
  • Project supervision at undergraduate and postgraduate levels MPhil and PhD.

Qualifications

Engineer, DEA, PhD

Honours and awards

  • The Marquise index Who’s Who in the World, Editions 2008
  • The Dictionary of International Biography, 34th edition, Cambridge 2008
  • Nominated for a DMU Vice Chancellors Distinguished Teaching Award.

Conference attendance

Kinetic tools for the investigation of unimolecular and bimolecular photoreactions of drugs. Potential for actinometry. 7th International Meeting on the Photostability of Drugs and Drug Products (1–3 October 2008). M Maafi, London.

A semi empirical kinetic law for AB(2φ) systems. usefulness for direct actinometry. XXII IUPAC Symposium on photochemistry (28 July–1 August 2008), M Maafi, Gothenburg, Sweden.

A complete elucidation of AB(2k,1φ) ThermoPhoto-Chromic Kinetics. A Mathematically Analytical method based on Pure Kinetic Data. XXII IUPAC Symposium on photochemistry (28 July–1 August 2008), M Maafi, R G Brown, Gothenburg, Sweden.

Current research students

First supervisor for the following PhD students: Damerdji Wassila, Lok Yan Lee, Leonie Hough.

Externally funded research grants information

In preparation: a research project on drugs stability.

Professional esteem indicators

E-Journal of chemistry and a referee for several journals.

Case studies

Citation in international journals in the year 2011.

Angewandte Chemie - International Edition : Imprinting chemical and responsive micropatterns into metal-organic frameworks, Han S, Wei Y, Valente C, Forgan R S, Gassensmith J J, Smaldone R A, Nakanishi H, (...), Grzybowski B A, 50 (1), pp 276-279 2011.

Journal of Photochemistry and Photobiology C: Photochemistry Reviews : Quantitative analysis of the dynamic behaviour of photochromic systems. Delbaere, S, Vermeersch,G, Micheau,J-C, 12(2), pp 74–105 2011.

Phys Chem Chem Phys: Tuning of switching properties and excited-state dynamics of fulgides by structural modifications, Ron Siewertsen, Frank Strübe, Jochen Mattay, Falk Renth and Friedrich Temps, 13, pp 3800-3808 2011.

European Journal of Organic Chemistry : Photochromism of Rotation-Hindered Furylfulgides Influenced by Steric Modifications, Frank Strübe, Ron Siewertsen, Frank D. Sönnichsen, Falk Renth, Friedrich Temps, Jochen Mattay, pp 1947–1955 2011.

Chemical Physics Letters : Deciphering the host–guest chemistry of Acridine Yellow and Cucurbit[7]uril: An integrated spectroscopic and calorimetric study, Brotati Chakraborty, Samita Basu, 507(1-3), pp 74-79 2011.

Photochemistry : Photochemistry of aromatic compounds. Mizuno,K, 38, pp 168-209 2011.

Journal of Molecular Liquids: Solvent effect on the spectroscopic properties of 6MAMC and 7MAMC, Melavanki,R M, Patil,N R, Kapatkar,S B, Ayachit,N H, Umapathy,S, Thipperudrappa,J, Nataraju,A R, 158 (2), pp 105-110 2011.

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy : Comments on the determination of excited state dipole moment of molecules using the method of solvatochromism A Kawski, P Bojarski, 82 (1), pp 527-528 2011.

Photochemistry: Photochemistry of aromatic compounds. Mizuno,K, 38, pp 168-209 2011.

Photochemistry: Alkenes, alkynes, dienes, polyenes. Tsuno,T, 38, pp 110-142, 2011.

Book: Dey,D, Kumar Sarangi,M and Basu,S (2011) Chapter 9 : Hydrogen Bonding on Photoexcitation, in Hydrogen Bonding and Transfer in the Excited State, Volume I & II (eds K.-L. Han and G.-J. Zhao), John Wiley & Sons Ltd, Chichester, UK.

Book : Timcheva,I and Nikolov,P (2011) Chapter 12 : Intermolecular Hydrogen Bonding in the Fluorescence Excited State of Organic Luminophores Containing Both Carbonyl and Amino Groups, in Hydrogen Bonding and Transfer in the Excited State, Volume I & II (eds K.-L. Han and G.-J. Zhao), John Wiley & Sons Ltd, Chichester, UK.

Journal of Advanced Research in Physics: Solvent effects on the electronic absorption and fluorescence spectra, Mihaela Homocianu1, Anton Airinei and Dana Ortansa Dorohoi, 2(1), 011105, 2011.

Journal of Photochemistry and Photobiology A: Chemistry: Chemical reactions of benzophenone photoirradiated in 1,2-polybutadiene. Barboiu,V, Avadanei,M I, 222(1), pp 170-179 2011.

Journal of Molecular Liquids: On the ground and excited state dipole moments of dansylamide from solvatochromic shifts of absorption and fluorescence spectra. Tewari,N, Joshi,N K, Rautela,R, Gahlaut,R, Joshi,H C, Pant,S, 160(3), pp 150-153 2011.

Research Advance in the Effects of β-Cyclodextrin and Its Derivatives on Fluorescence Enhancement, Zhang Min, Zhang Yu-hao, Ma Liang , Vol 32, No 01 297 2011.