Professor Joan Taylor

• Pharmaceutical Technologies
• INsmart group

Prof Taylor has led the development of a totally implantable artificial pancreas for the treatment of insulin dependent diabetes and the setting up of an exercise physiology lab in DMU for the study of exercise physiology in diabetes patients.

• Insulin physico-chemistry
• Diabetes control
• Drug delivery
• Rheometry (viscosity of gels and sols)
• Engineering and design of devices for drug delivery
• Physiological parameters for exercise in diabetes.

• Compounding of medicines
• Pharmaceutics and formulation
• Biopharmaceutics, with focus on eye and brain
• Targeted drug delivery
• Delivery of insulin in diabetes.

BSc, MSc, PhD, GPhC MRPSGB

• Pharmacy MPharm
• Pharmaceutical and Cosmetic Science and associated MSc
• MSc degree QbD.

• Member of the Royal Pharmaceutical Society of Great Britain
• Member of the General Pharmaceutical Council (GPhC)

Membership of GPhC is licence to practise.

• CRS in Quebec - July 2012
• APS in Nottingham - Sept 2012
• Diabetes Technology Meeting, Bethesda - Nov 2012
• Development of Channel 4 programme Body Build about artificial organs for broadcast in UK and US and an exhibition in Kensington Science Museum and Washington Smithsonian – Winter 2012
• Development of NHS TV programme for broadcast - Winter 2012.

Posters

Taylor, M. & Sahota, T. Glucose-sensitive insulin delivery in vivo - an artificial pancreas? (Poster) 3rd International conference on advanced treatments and technologies (ATTD) Basel Feb 2010.

Sahota T. S. and Taylor M. J. Competitive displacement of blue dextran by cibacron blue in dextran albumin gels? (Poster) Intern. Symp. Control. Rel. Bioact. Mater, Controlled Release Society, Inc. Portland, Oregon 2010.

Invited presentations

Taylor M. J. An overview of the role of closed loop control in diabetes Intern. Symp. Control. Rel. Bioact. Mater, Controlled Release Society, Inc. New York 2008 (invited talk, abstract printed in Journal of Controlled Release).

Taylor M. J. Automated basal–boost insulin delivery British Pharmaceutical Conference (Science) (invited talk, abstract printed in Journal of Pharmacy & Pharmacology) Sept 2009.

Taylor, M. & Sahota, T. Devising an automated basal–boost insulin delivery system (invited talk) Bioengineering ’09 Conference, Oxford Sept 2009.

Taylor, M. & Sahota, T. Devising an automated basal–boost insulin delivery system (invited talk) Polymer Carriers for Controlled Drug Delivery at the 11th Pacific Polymer.
Conference series (PPC11) ’09 Conference, Cairns, N. Queensland December 2009.

Taylor, M. & Sahota, T. Devising an automated basal–boost insulin delivery system (invited talk) Australasian Pharmaceutical Science Association (APSA) & Aus-CRS scientific meeting ’09, Hobart, Tasmania Dec 2009.

Taylor M. J. In Pursuit of Closed Loop Delivery of Insulin. South East Health Technologies Alliance (SEHTA) Monitoring and Managing Drug Delivery –(no abstract) 2009.

Taylor M. J. Novel Closed Loop Delivery of Insulin. Royal Society of Medicine, Wimple St, London (no abstract) 2010 Direct link to video of lecture http://www.rsmvideos.com/videoPlayer/?vid=127

Taylor M. J. Novel Closed Loop Delivery of Insulin. Leicester Royal Infirmary Childrens Diabetes Group 2011.

Taylor M. J. Modern Methods of Insulin Delivery Association of British Clinical Diabetologists (ABCD) Leeds April 2012.

• Broadcasts about diabetes and the artificial pancreas.
• Available for consultancy about drug/protein/insulin delivery except in COI cases
• Available to teach or consult using rheometry (state of art equipment).

1st Supervisor to:

• Ahmed Alsabih
• Mohammed Albihed
• Dolly Jacob
• E-Ching Luo

2nd Supervisor to:

• Adeola Kola-Mustapha

• Development of rodent model for testing artificial pancreas Lachesis - £248k investment and research support - 2004
• Development of gel for artificial pancreas NEAT - £189k - 2004
• Development of refillable artificial pancreas and pilot testing in pig model - NEAT £277k - 2008
• Medical engineering for refillable pancreas Prospect IP - £55k - 2008
• Additional for due diligence Lachesis - £5k - 2008
• Development of pig model Edith Murphy Foundation - £50k research funding with 50% matched - 2008
• Osmotic pressure and stability testing for gel in artificial pancreas Edith Murphy Foundation - £50k research funding with 50% matched - 2011
• Business development, partner search, regulatory development for INSmart artificial pancreas Edith Murphy Foundation - £200 research funding - 2011

Nanoparticle for CNS targeting HEIF - £10k - 2011

Patents 1993-2012

Taylor, MJ Patent Application 9126301.2 (Improving Effectiveness of Drugs) (re-filed in December 1991, transferred to Pharmakopius International in 1994 and now lapsed.

Taylor, M. (1992). Drug System. Filing & published July 1993. Patent Application 9200638.6 (Drug System I) Patent WO 93/13803. Granted US (5,830,506 1998) (divisional 09/124,694 still pending late 2004). Europe EP0626862 B11999 granted Sept 1 1999, De Montfort University. Now being allowed to lapse as 2001 patent granted.

Taylor, M. (1993). Drug System II. Filing & published January 1995. Patent Application 9313484.9. Patent WO 95/01186. Granted US (5,902,607 1999) (divisional 09/124,445 or alternatively US6410053 granted 2002). Granted in Europe –EP0706401 Nov 27 2002, De Montfort University. Now being allowed to lapse as 2001 patent granted.

Taylor, M. (2001). Glucose Sensing Gel. (10 July 2001 filing; PCT filed July 2002, issued 23 01 03), GB.0116860.8, De Montfort University.(Granted in Europe Dec 2010 and in the US in 2012).

Taylor, M. (2012). Three new patents relating to the device in process of filing. Details available sumer 2012

Information about the Artificial Pancreas
The artificial pancreas was developed by Professor Joan Taylor. It is made of a metal casing that holds a holds a gel filled barrier inside. http://www.informationaboutdiabetes.com/news/diabetes-research/information-about-the-artificial-pancreas

Leicester develop new artificial pancreas
A researcher from Leicester has developed an artificial pancreas which could put a stop to daily injections.
www.drwf.org.uk/tabid/705/View/true/ParentId/242/Default.aspx

Artificial pancreas offers hope to diabetics
A researcher has developed an artificial pancreas that she says could revolutionise the treatment of diabetes.
www.independent.ie/.../artificial-pancreas-offers-hope-to-diabetics-2341282.html

Artificial pancreas | Facebook
Professor Joan Taylor of De Montfort University has patented a new type of artificial pancreas.
http://www.facebook.com/pages/Artificial-pancreas/102178366490028